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ea0081ep657 | Pituitary and Neuroendocrinology | ECE2022

Pathomorphological markers of somatotroph neuroendocrine tumors predicting the treatment outcome in acromegaly

Tomasik Agnieszka , Stelmachowska-Banaś Maria , Maksymowicz Maria , Czajka-Oraniec Izabella , Raczkiewicz Dorota , Zieliński Grzegorz , Kunicki Jacek , Zgliczyński Wojciech

Background: Transsphenoidal adenomectomy of GH-secreting pituitary tumour is a first-line treatment of acromegaly. Pharmacological treatment is recommended if surgery did not lead to disease remission. Pathological assessment of postoperative tissue provides clinicians with valuable information on the disease course.Aim: The aim of this study was to assess whether clinical, imaging, and pathological characteristics can predict surgical remission and resp...